Kobe is the 6th largest city in Japan and famous for its signature marbled beef. The Ikuta Shrine there is among Japan's oldest shrines, dating back to the 3rd century. Kobe is also the gateway to Mount Rokko, accessible by antique cable cars, and the outdoor hot springs of Arima Onsen. Other sites include the Sake Breweries, the Earthquake Museum, and Sorakuen Garden.

The main gateway to Shikoku Island and an important focal point for the island's rail and road transit systems, Takamatsu, on Japan's scenic Inland Sea, has been a political and economic center since the Edo period. Among the attractions here is Ritsurin Garden, created during the Edo period, and especially popular during spring for the cherry blossoms and autumn for the fall foliage. Takamatsu Symbol tower has several observation decks providing panoramic views of the sea and landscapes.

This picturesque port city is one of Windstar's iconic hidden harbors.  Tomonoura is part of the Setonanikai National Park and features an endearing old-fashioned townscape. One of its thriving industries is the production of "homeishu," a medicinal liquor with 16 different herbs in it, said to promote longevity.

Located on the island of Kyushu, Karatsu is one of the closest Japanese cities to the Korean Peninsula. Karatsu Castle is the main attraction here. Built in 1608, it houses a museum of the castle's history and Karatsu ceramics. Karatsu is also known for its pottery which can be viewed at the Karatsu-yaki Pottery Gallery. Also worth visiting is the Karatsu Hikiyama Exhibition Hall which displays the 14 floats used in the annual Karatsu Kunchi Festival in November.

The second largest city in South Korea is a popular leisure destination due to the nearby hot springs. It is home to many famous beaches that lure visitors from around the world and the UNESCO site of Gyeongju an outdoor museum that was once the capital of the Silla Kingdom and holds many architectural points of interest including ornate temples.   Also of interest is South Korea's largest temple, Tongdosa Temple, renowned for having no outdoor statues.

Cruise around the island of Hashima, abandoned over 50 years ago when the coal mining that flourished there suddenly ran out. The mining company shut the mine down and the island has been a ghost town ever since.

Notable for the nuclear attack it suffered during WWII, Nagasaki has memorialized the event at the city's Atomic Bomb Museum and Peace Memorial Park. The museum tells the story of the events leading up to the bombing and the park, located at the center of the bomb blast, houses a beautiful 30-foot tall fountain symbolizing peace. Other highlights to see are the Glover Gardens and Dejima Museum, which was originally an artificial island.

The seaside city of Kagoshima is best known for Sakurajima, an active volcano facing Kinko Bay. Take a tour to the Shiroyama Observatory or to the peaceful Edo-period Sengamen Japanese Garden. Visit the Ishibashi Park and the three Edo-period stone bridges or travel to the nearby village of Chiran to see the well-preserved Samurai Houses and the Chiran Peace Museum, exploring the background of kamikaze pilots.